2022 Registration Preview

Are you ready? Registration for Pedal the Cause 2022 opens March 1!

We’re gearing up for another amazing year of creating a world without cancer Friday, September 23 through Sunday, September 25 in Chesterfield. Join us for scenic rides, amazing food, celebration and more!

Sign up early for savings on registration fees and fundraising requirements.
Whether you ride, spin, volunteer or participate virtually through Inspired, you’ll be making a difference in the fight against cancer.

As always, 100% of funds raised from Pedal the Cause support cancer research at Siteman Cancer Center and Siteman Kids at St. Louis Children’s Hospital.

2022 Courses

With courses ranging from 10-100 miles over two days, there’s something for everyone!

We have some awesome new rides to choose from this year as well as classic favorites. Check out the beautiful Ted Jones Katy Classic or the all-new flat century ride option. The 30-mile Pedal Pacer—a big hit in 2021—is offered on both Saturday and Sunday.

Up for the ultimate challenge? Riders who complete both century rides—the Big Muddy Century on Saturday and The Beast on Sunday—will receive a special gift commemorating their achievement. A few bragging rights are in order!

Spin Zone

There’s nothing like the incredible energy of the Pedal the Cause Spin Zone! Choose from three different spin sessions Sunday, September 25.

Ready for more? Choose two or three hours of spin and commit to a higher fundraising requirement.


With our Inspired participation option, choose your own activity to complete on Pedal weekend from anywhere in the world!

Whether biking, spinning, running, walking or tackling a challenge of your own creation, you’ll be helping create a world without cancer.

Kids Challenge

The Pedal the Cause Kids Challenge returns Saturday, September 17 to the Chesterfield Mall.

Two shift times will be offered for kids ages 5-8; kids ages 9-12 can choose from three available shift times. Enjoy food and family-friendly activities all day!

Taste the Cause

It’s back! After a two-year hiatus, we’re thrilled to bring back one of the most fun (and delicious!) Pedal events.

Join some of St. Louis’ top chefs Friday, September 23 for Taste the Cause sponsored by True Refrigeration, followed by the Pedal the Cause Inspirational Program.

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